Hypoxia and HIF signalling
Pathway9 papersGO 0001666
- Animals3
- Cells1
- In silico1
Latest
9AnimalsCellular senescence
Jianwei Shoutai Pills reduce uterine aging and pregnancy loss in aged mice
The herbal formula delayed thymic involution, restored regulatory T cell function, and improved maternal-fetal immune tolerance by altering metabolic signaling in aging female mice.
Depp1 drives muscle loss under fasting and low oxygen in mice
The study reveals that the protein localizes to mitochondria to regulate autophagy and mitochondrial degradation during nutrient and oxygen limitation.
AnimalsCellular senescence
Arsenic triggers heart senescence in mice while quercetin counteracts the damage
Exposure to environmental arsenic caused heart dysfunction via the p53 and p21 pathway, which quercetin treatment reversed in cultured rat cardiomyoblasts.