MitochondriaCells28 Sep 2026

CCN1 upregulation in diabetic wounds suppresses PINK1/Parkin-mediated mitophagy in dermal fibroblasts by regulating HIF-1α protein stability under decompensated hypoxic conditions

Cellular Signalling

The paper

Chen T, Yang P, Xie Y et al.

Cellular Signalling · 27 Sep 2026

doi.org/10.1016/j.cellsig.2026.112909 PubMed

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CCN1 upregulation in diabetic wounds suppresses PINK1/Parkin-mediated mitophagy in dermal fibroblasts by regulating HIF-1α protein stability under decompensated hypoxic conditions

The paper

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Cardiolipin loss drives muscle fiber shifts during aging via a nuclear receptor

Early-life mitochondrial DNA mutations drive age-related pathology in mice

Inhibiting miR-128-3p restores muscle mass and function in aged mice

Prodh2 inhibition alleviates muscle atrophy and restores strength in COPD mice

Depp1 drives muscle loss under fasting and low oxygen in mice