HIF1A

1. HIF1A induces age-related pathology.

   Reviewpersistent or unresolved signalling

   Oxygen sensing governs tissue regeneration, degeneration, and ageing · Trends in molecular medicine · 30 Sep 2026

1. HIF1A induces tissue regeneration.

   Reviewtransient activity

   Oxygen sensing governs tissue regeneration, degeneration, and ageing · Trends in molecular medicine · 30 Sep 2026

1. CCN1 decreases HIF1A in human cells.

   Cellshuman dermal fibroblasts

   CCN1 upregulation in diabetic wounds suppresses PINK1/Parkin-mediated mitophagy in dermal fibroblasts by regulating HIF-1α protein stability under decompensated hypoxic conditions · Cellular signalling · 27 Sep 2026

CCN1 →