Humans·Peer-reviewed
In an older Scottish cohort, epigenetic age and brain volume outmatched plasma proteomic organ clocks for predicting long-term all-cause mortality.
Aging cell · 1 Oct · Pyrgioti M, Eguiagaray IM, Redmond P et al.
Humans·Peer-reviewed
Cell counts explain less variation in age acceleration and only modestly affect its links to mortality and 176 incident health outcomes.
Genome medicine · 2 Oct · Jonkman TH, Richmond A, BIOS Consortium et al.
In silico·Preprint
bioRxiv · 1 Oct · Goryanin I, Goryanin I, Damms B
Humans·Peer-reviewed
Nutrition and cancer · 1 Oct · Ye Q, Jiang S, Chen J et al.
Humans·Preprint
Multi-omics clocks across fourteen organs reveal divergent molecular programs and uncover thirteen candidate genes separating age acceleration from mortality.
Research Square · 30 Sept · Na R, Shi C, Ruan X et al.
In silico·Peer-reviewed
Imperfect maintenance of developmental chromatin constraints causes age-associated DNA methylation gains predominantly at polycomb-regulated genomic regions across mammalian tissues.
Nature · 30 Sept · Yücel AD, Molière A, Gladyshev VN
Humans·Preprint
Qeios · 30 Sept · Xiong J
Humans·Preprint
The systems pharmacology model splits biological age into organ axes, revealing that pharmacological drops in inflammation may not translate to expected risk reductions.
bioRxiv · 30 Sept · Goryanin I, Damms B, Goryanin I
Humans·Preprint
A DNA-methylation measure of pubertal development correlates with established epigenetic clocks and predicts mortality and disease in two large adult cohorts.
medRxiv · 30 Sept · Wu Q, Gibbs SF, deSteiguer AJ et al.
Humans·Peer-reviewed
GeroScience · 30 Sept · Caunca MR, Kezios K, Schneider ALC et al.
Humans·Peer-reviewed
An analysis of NHANES data identifies source-dependent effects and an optimal serum iron window between 15.2 and 18.8 micromoles per liter.
Asia Pacific journal of clinical nutrition · 1 Oct · Cao Q, Feng-Gao Y, Chen Y et al.
Humans·Peer-reviewed
Maturitas · 25 Sept · Zhao H, Xu Y, Gao Y et al.
Humans·Peer-reviewed
Journal of electrocardiology · 28 Sept · Khalil ME, Rickard J, Qadura M