Lipopolysaccharide

Intervention2 papers1 finding

Outcomes

Proinflammatory cytokine secretion

no changein cells1

1 study

Lipopolysaccharide has no effect on proinflammatory cytokine secretion in cells.
Cellsduring agingbone marrow-derived macrophages
NLRP3 inflammasome activity shifts toward regulating cell fate in aged macrophages · Bulletin of experimental biology and medicine · 28 Sep 2026

Inhibiting the NLRP3 inflammasome with MCC950 reduced apoptosis but increased senescence in aged bone marrow-derived macrophages.

Bulletin of Experimental Biology and Medicine · Blagova AV et al.

AnimalsMitochondria26 Sep

Inhibiting the kinase reduced p62 UFMylation to promote ubiquitination and mitochondrial clearance, alleviating cognitive deficits in mice.

Biochemical Pharmacology · Dong YR et al.