Sqstm1
GeneMus musculus5 papersMGI 107931NCBI Gene 18412Taxon 10090
- Animals5
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5Animals
Dietary CoQ10 improves megakaryocyte function and reduces platelet hyperreactivity in aging mice
The supplement boosted autophagy via COPS3, enhancing megakaryocyte maturation and polyploidization without altering baseline platelet counts.
AnimalsBrain aging
Ghrelin alleviates aging-related cognitive impairment by restoring microglial autophagy
Researchers identified ghrelin as a key metabolic factor that reduces microglial senescence and inflammation through the SHBG/JNK1/Beclin1 signaling axis.
AnimalsMitochondria
Blocking Src kinase reduces neuroinflammation by activating microglial mitophagy in mice
Inhibiting the kinase reduced p62 UFMylation to promote ubiquitination and mitochondrial clearance, alleviating cognitive deficits in mice.