Mitochondrial reactive oxygen species

Biomarker5 papers1 finding

Interventions

Icariin

downin mice1

1 study

Icariin decreases mitochondrial reactive oxygen species in mice.
Animals
Icariin improves cognition and reduces neuroinflammation by promoting mitophagy in mice · Chinese journal of natural medicines · 1 Oct 2026

AnimalsMitochondriaYesterday

TNF-alpha triggers a mitochondrial immune pathway via Prodh2 that damages myoblasts, while silencing the enzyme restores muscle strength in mice.

Aging Cell · Chen G et al.

Blocking the cytokine with secukinumab reduced cartilage senescence and slowed osteoarthritis progression in a mouse model.

Oral Diseases · Zhu M et al.

The flavonoid engages PINK1 to curb microglial pyroptosis and mitochondrial stress in models of Alzheimer's disease.

Chinese Journal of Natural Medicines · Fan L et al.

ReviewMolecular Neurobiology

1 Oct

ReviewFrontiers in Molecular Neuroscience

1 Oct

Animals30 Sep

Targeting this pathway curbs mitochondrial oxidative stress and pericyte activation to partially restore auditory function in mouse models.

Aging Cell · Xu R et al.

ReviewAntioxidants

26 Sep