Mitochondrial Redox Failure Links Senescence-like Foam Cell Stress to Ferroptosis and Plaque Non-Resolution in Atherosclerosis
Abstract · CC BY
Foam cells are central to atherosclerotic plaque development, but their pathological significance in advanced lesions extends beyond lipid accumulation.
- Cellular senescence
- Disabled macroautophagy
- Mitochondrial dysfunction
- Ferroptosis
- Mitophagy
- Oxidative stress and ROS signalling
- Atherosclerosis
- Reactive oxygen species
The paper
Mitochondrial Redox Failure Links Senescence-like Foam Cell Stress to Ferroptosis and Plaque Non-Resolution in Atherosclerosis
Khin PP, Mo HMM, Kim CS
Antioxidants · 25 Aug 2026