Amyloid pathology
Disease2 papers1 finding
- Animals2
Interventions
1Mitoq
downin mice1
1 study
Mitoq
downin mice1
Mitoq decreases amyloid pathology in mice.
Animals5XFAD mice with established Alzheimer's disease pathology
Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice · Aging and disease · 22 Sep 2026
Latest
3Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice
Treatment with astrocyte-conditioned solution also rescued cognitive deficits and lowered inflammation in mouse models of Alzheimer's disease.
AnimalsMitochondria
Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice
Oral treatment improved behavioral deficits, suppressed amyloid plaques, lowered neuroinflammation, and restored mitochondrial quality control in mice with established disease.
AnimalsmTOR & rapamycin
Chronic stress accelerates Alzheimer pathology in mice by hyperactivating mTORC1
Inhibiting mTORC1 restored autophagy, reduced amyloid accumulation, and corrected circuit desynchronization and behavioral deficits in stressed Alzheimer model mice.