Mitoq
Intervention1 paper6 findingsPubChem 11388331ChEBI 234429
In a mouse model of Alzheimer's disease, Mitoq decreases amyloid pathology, pTau622, and oxidative DNA damage, whilst activating mitophagy and improving novelty-related exploration. Reviews also describe it reducing mitochondria-derived ROS.
- Animals1
Outcomes
6Mitochondria-derived ROS
downin reviews1
1 study
Mitochondria-derived ROS
downin reviews1
Mitoq decreases mitochondria-derived ROS.
Review
Therapeutic potential of MitoQ, a mitochondria-targeted antioxidant, in age-related physiological dysfunction · GeroScience · 28 Sep 2026
Mitophagy
upin mice1
1 study
Mitophagy
upin mice1
Mitoq activates mitophagy in mice.
Animals5XFAD mice with established Alzheimer's disease pathology
Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice · Aging and disease · 22 Sep 2026
Oxidative DNA damage
downin mice1
1 study
Oxidative DNA damage
downin mice1
Mitoq decreases oxidative DNA damage in mice.
Animals5XFAD mice with established Alzheimer's disease pathology
Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice · Aging and disease · 22 Sep 2026
pTau622
downin mice1
1 study
pTau622
downin mice1
Mitoq decreases pTau622 in mice.
Animals5XFAD mice with established Alzheimer's disease pathology
Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice · Aging and disease · 22 Sep 2026
Amyloid pathology
downin mice1
1 study
Amyloid pathology
downin mice1
Mitoq decreases amyloid pathology in mice.
Animals5XFAD mice with established Alzheimer's disease pathology
Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice · Aging and disease · 22 Sep 2026
Novelty-related exploration
upin mice1
1 study
Novelty-related exploration
upin mice1
Mitoq improves novelty-related exploration in mice.
Animals5XFAD mice with established Alzheimer's disease pathology
Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice · Aging and disease · 22 Sep 2026
Latest
3Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice
Oral treatment improved behavioral deficits, suppressed amyloid plaques, lowered neuroinflammation, and restored mitochondrial quality control in mice with established disease.