Malondialdehyde
Biomarker12 papers6 findings
Various natural compounds and ALDA-1 reduce levels of the lipid peroxidation biomarker malondialdehyde across studies in mice, worms and female flies.
- Animals7
- Model organisms3
- Cells2
Interventions
6Cedrus deodara flavonoids
downin mice1
1 study
Cedrus deodara flavonoids
downin mice1
Cedrus deodara flavonoids decrease malondialdehyde in mice.
Animalsozone exposuredeep eutectic solvent extractserum14 days
Green Extraction of Flavonoids from Cedrus deodara Pollen with Deep Eutectic Solvents and Their Potential Anti-Senescence Properties · Research Square · 29 Sep 2026 · Preprint
Panax ginseng + schisandra chinensis
downin mice1
1 study
Panax ginseng + schisandra chinensis
downin mice1
Panax ginseng + schisandra chinensis decreases malondialdehyde in mice.
Animalscompared with model miceco-decoction
Ginseng-Schisandra ameliorates D-galactose-induced cognitive impairment in mice: Evidence from gut microbiota and metabolomic analyses · Fitoterapia · 28 Sep 2026
Perilla frutescens
downin worms1
1 study
Perilla frutescens
downin worms1
Perilla frutescens decrease malondialdehyde in worms.
Model organismsethyl acetate leaf extract
Perilla frutescens extract reduces fat accumulation and promotes longevity in Caenorhabditis elegans via modulation of the insulin/IGF-1 signaling pathway · Biogerontology · 26 Sep 2026
ALDA-1
downin mice1
1 study
ALDA-1
downin mice1
ALDA-1 decreases malondialdehyde in mice.
AnimalsD-galactose-induced aginghippocampus
Alda-1 Alleviates the Cognitive Deficits in D-galactose-induced Aging Mice by Regulating Oxidative Stress, Neuroinflammation, and Mitochondrial Biogenesis · The journals of gerontology. Series A, Biological sciences and medical sciences · 25 Sep 2026
Physalis pubescens polysaccharides
downin flies1
1 study
Physalis pubescens polysaccharides
downin flies1
Physalis pubescens polysaccharides decrease malondialdehyde in flies.
Model organismsselenylated fruit polysaccharide derivativefemales
Selenylated Physalis pubescens polysaccharide extends lifespan and activates Nrf2/HO-1-mediated antioxidant defense: structural elucidation and multi-target mechanism · Bioorganic chemistry · 23 Sep 2026
Gracilariopsis lemaneiformis polysaccharides
downin worms1−73%
1 study
Gracilariopsis lemaneiformis polysaccharides
downin worms1−73%
Gracilariopsis lemaneiformis polysaccharides decrease malondialdehyde in worms (-73.4%).
“redox homeostasis (SOD activity +19.5%, MDA content -73.4% for GP-H)”
Model organismsin wild-type N2 wormsfermented with Lactiplantibacillus plantarum HJ-S2
Strain-Dependent Fermentation Enhances the Bioactivity of Gracilariopsis lemaneiformis Polysaccharide-Rich Fractions · Foods (Basel, Switzerland) · 16 Sep 2026
Latest
12Gastrodia elata polysaccharide extends worm lifespan and mitigates age-related deficits in mice
The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.