FOXO signalling
Pathway10 papers1 finding
- Animals3
- Model organisms4
- In silico1
Interventions
1Turnera diffusa polysaccharides
upin model organisms1
1 study
Turnera diffusa polysaccharides
upin model organisms1
Turnera diffusa polysaccharides activate FOXO signalling.
Model organisms
Turnera diffusa polysaccharides promote healthy aging through conserved stress response regulation and metabolic remodeling across multiple aging models · Biogerontology · 25 Sep 2026
Latest
10FOXO3 overexpression delays primordial follicle activation in chickens
Overexpressing the transcription factor kept avian follicles dormant and suppressed PI3K and AKT signaling during early ovarian development.
Depp1 drives muscle loss under fasting and low oxygen in mice
The study reveals that the protein localizes to mitochondria to regulate autophagy and mitochondrial degradation during nutrient and oxygen limitation.
Erigeron breviscapus extends worm lifespan and reduces senescence markers in mice
The herbal extract activates AMPK-SIRT1 signaling, enhancing antioxidant defenses and modulating apoptosis to alleviate tissue aging across both model organisms.