daf-16
GeneCaenorhabditis elegans4 papers2 findingsNCBI Gene 172981Taxon 6239
- Animals1
- Model organisms3
Interventions
1Perilla frutescens
upin worms1
1 study
Perilla frutescens
upin worms1
Perilla frutescens activate daf-16 in worms.
Model organismsethyl acetate leaf extract
Perilla frutescens extract reduces fat accumulation and promotes longevity in Caenorhabditis elegans via modulation of the insulin/IGF-1 signaling pathway · Biogerontology · 26 Sep 2026
Effects
1Lifespan
is required forin worms1
1 study
Lifespan
is required forin worms1
daf-16 is required for lifespan in worms.
Model organismsfor EBHM-induced lifespan extension
Erigeron breviscapus extends worm lifespan and reduces senescence markers in mice · Biogerontology · 25 Sep 2026
Latest
4Erigeron breviscapus extends worm lifespan and reduces senescence markers in mice
The herbal extract activates AMPK-SIRT1 signaling, enhancing antioxidant defenses and modulating apoptosis to alleviate tissue aging across both model organisms.