Gracilariopsis lemaneiformis polysaccharides

1. Gracilariopsis lemaneiformis polysaccharides extend lifespan in worms.

   “Lifespan extension also persisted in a daf-16 loss-of-function background, supporting contributions from complementary longevity networks.”

   Model organismsin a daf-16 loss-of-function background

   Strain-Dependent Fermentation Enhances the Bioactivity of Gracilariopsis lemaneiformis Polysaccharide-Rich Fractions · Foods (Basel, Switzerland) · 16 Sep 2026

2. Gracilariopsis lemaneiformis polysaccharides extend lifespan in worms (+21.21% mean lifespan).

   “In wild-type N2 worms, GP, GP-D, and GP-H extended mean lifespan by 8.61%, 14.70%, and 21.21%, respectively”

   Model organismsin wild-type N2 wormsfermented with Lactiplantibacillus plantarum HJ-S2

   Strain-Dependent Fermentation Enhances the Bioactivity of Gracilariopsis lemaneiformis Polysaccharide-Rich Fractions · Foods (Basel, Switzerland) · 16 Sep 2026

3. Gracilariopsis lemaneiformis polysaccharides extend lifespan in worms (+14.70% mean lifespan).

   “In wild-type N2 worms, GP, GP-D, and GP-H extended mean lifespan by 8.61%, 14.70%, and 21.21%, respectively”

   Model organismsin wild-type N2 wormsfermented with Lacticaseibacillus casei DS31

   Strain-Dependent Fermentation Enhances the Bioactivity of Gracilariopsis lemaneiformis Polysaccharide-Rich Fractions · Foods (Basel, Switzerland) · 16 Sep 2026

4. Gracilariopsis lemaneiformis polysaccharides extend lifespan in worms (+8.61% mean lifespan).

   “In wild-type N2 worms, GP, GP-D, and GP-H extended mean lifespan by 8.61%, 14.70%, and 21.21%, respectively”

   Model organismsin wild-type N2 wormsunfermented polysaccharide-rich fraction

   Strain-Dependent Fermentation Enhances the Bioactivity of Gracilariopsis lemaneiformis Polysaccharide-Rich Fractions · Foods (Basel, Switzerland) · 16 Sep 2026

1. Gracilariopsis lemaneiformis polysaccharides decrease malondialdehyde in worms (-73.4%).

   “redox homeostasis (SOD activity +19.5%, MDA content -73.4% for GP-H)”

   Model organismsin wild-type N2 wormsfermented with Lactiplantibacillus plantarum HJ-S2

   Strain-Dependent Fermentation Enhances the Bioactivity of Gracilariopsis lemaneiformis Polysaccharide-Rich Fractions · Foods (Basel, Switzerland) · 16 Sep 2026

Malondialdehyde →

1. Gracilariopsis lemaneiformis polysaccharides increase superoxide dismutase in worms (+19.5%).

   “redox homeostasis (SOD activity +19.5%, MDA content -73.4% for GP-H)”

   Model organismsin wild-type N2 wormsfermented with Lactiplantibacillus plantarum HJ-S2

   Strain-Dependent Fermentation Enhances the Bioactivity of Gracilariopsis lemaneiformis Polysaccharide-Rich Fractions · Foods (Basel, Switzerland) · 16 Sep 2026

Superoxide dismutase →

1. Gracilariopsis lemaneiformis polysaccharides improve locomotion in worms.

   “improved heat and oxidative stress survival (median survival +44% and +20% for GP-H, respectively), locomotion, redox homeostasis”

   Model organismsin wild-type N2 worms

   Strain-Dependent Fermentation Enhances the Bioactivity of Gracilariopsis lemaneiformis Polysaccharide-Rich Fractions · Foods (Basel, Switzerland) · 16 Sep 2026