IL-1β
Biomarker4 papers
- Animals2
- Cells1
Latest
10AnimalsBrain aging
Gastrodia elata polysaccharide extends worm lifespan and mitigates age-related deficits in mice
The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.
AnimalsMitochondria
Icariin improves cognition and reduces neuroinflammation by promoting mitophagy in mice
The flavonoid engages PINK1 to curb microglial pyroptosis and mitochondrial stress in models of Alzheimer's disease.
AnimalsCellular senescence
Lack of the AT2R receptor accelerates cardiac senescence and fibrosis in aging mice
Mice lacking the receptor also showed higher inflammation, elevated DNA damage, and a five-month reduction in median lifespan.