Berberine as a multi-hallmark modulator of aging: From AMPK and mitophagy to inflammaging and the SASP
- Cellular senescence
- Chronic inflammation
- Deregulated nutrient-sensing
- Disabled macroautophagy
- Loss of proteostasis
- Mitochondrial dysfunction
- AMPK signalling
- Autophagy
- Mitophagy
- NF-κB signalling
- NRF2–KEAP1 antioxidant response
- Senescence-associated secretory phenotype (SASP)
The paper
Berberine as a multi-hallmark modulator of aging: From AMPK and mitophagy to inflammaging and the SASP
Alanazi SM, Al-Kuraishy HM, Abdelaziz AM et al.
Fitoterapia · 28 Sep 2026