Increased mtDNA Polymorphism Level and Defective Mitophagy are Associated With Proinflammatory Activation in THP-1-Based Cybrids
- Chronic inflammation
- Disabled macroautophagy
- Mitochondrial dysfunction
- Mitophagy
- CCL2
- CXCL8
- IL1B
- IL6
- TNF
- IL-1β
- IL-6
- IL-8
The paper
Increased mtDNA Polymorphism Level and Defective Mitophagy are Associated With Proinflammatory Activation in THP-1-Based Cybrids
Zhuravlev AD, Nikiforov NG, Verkhova SS et al.
Frontiers in Bioscience · 1 Sep 2026