SLC25A33 overexpression

Intervention1 paper1 finding

Outcomes

Physical function

upin mice1

1 study

SLC25A33 overexpression improves physical function in mice.
“Conversely, exogenous IGF-1 or SLC25A33 overexpression attenuated these effects and partially restored auditory function.”
AnimalsAAV-mediatedcochlea
IGF-1 and SLC25A33 preserve cochlear blood barrier integrity in aged mice · Aging cell · 30 Sep 2026

Animals30 Sep

Targeting this pathway curbs mitochondrial oxidative stress and pericyte activation to partially restore auditory function in mouse models.

Aging Cell · Xu R et al.