Smad2
GeneMus musculus2 papersMGI 108051NCBI Gene 17126Taxon 10090
- Animals1
- Cells1
Latest
2CellsCellular senescence
Senescent prostate cancer cells drive stromal remodeling through TGF-beta signaling
Researchers found that senescent epithelial cells secrete TGF-beta1 to reprogram fibroblasts into a matrix-remodeling state, which senolytic treatment can blunt.
Animals
IGF-1 and SLC25A33 preserve cochlear blood barrier integrity in aged mice
Targeting this pathway curbs mitochondrial oxidative stress and pericyte activation to partially restore auditory function in mouse models.