GDF15
GeneHomo sapiens4 papersHGNC 30142NCBI Gene 9518Taxon 9606
- Human trial1
- Humans2
Latest
4HumansAging clocks
Proteomic organ clocks predict mortality but trail established physiological and epigenetic biomarkers
In an older Scottish cohort, epigenetic age and brain volume outmatched plasma proteomic organ clocks for predicting long-term all-cause mortality.
HumansBrain aging
Peripheral immune cell profiles predict cognitive decline in older adults
An immune risk score tracking immunosenescence correlated with markers of neural injury and neuroinflammation rather than classical amyloid or tau pathology.
Human trialAging clocks
Lifestyle modification reduces phenotypic age in adults with prediabetes
A six-month randomized trial in Arab adults found structured diet and exercise reduced biological age alongside metabolic markers.