Bone fracture

Disease2 papers1 finding

Animals1

Associations

1

Epigenetic age acceleration

upin humans1

1 study

Epigenetic age acceleration predicts bone fracture in humans (hazard ratios of 1.29-3.17 per standard deviation).
“In 1087 twins, epigenetic age acceleration predicted fracture and osteoporosis risk, with hazard ratios of 1.29-3.17 per standard deviation”
Reviewin twinsn = 1,087
Aging Biology of Bone-to-Tendon Healing and the Epigenetic Clock: A Biological-Age Readout of Rotator Cuff Healing Capacity · Biomedicines · 2 Sep 2026

Epigenetic age acceleration →

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Future directions of osteoanabolic therapies in osteoporosis: Integrating current anabolic agents and emerging senescence-targeted strategies

ReviewBest Practice & Research. Clinical Rheumatology

Yesterday

AnimalsPreprintInflammaging1 Oct

Cathelicidin peptide aids fracture healing in young mice but impairs it in aged mice

Depleting Camp accelerated bone callus formation in aged mice while delaying repair in young mice through P2X7 receptor and NLRP3 signaling.

bioRxiv · Nguyen T et al.

Aging Biology of Bone-to-Tendon Healing and the Epigenetic Clock: A Biological-Age Readout of Rotator Cuff Healing Capacity

ReviewBiomedicines

26 Sep