Telomere length
Biomarker11 papers7 findings
Human studies associate telomere length with Parkinson's disease, multiple system atrophy, diabetes, and drug-induced liver injury, whilst reviews link it to lithium. In female mice, high-intensity interval training increases hepatic telomere length.
- Humans5
- Animals1
- Model organisms1
Interventions
1High-intensity interval training
upin mice1
1 study
High-intensity interval training
upin mice1
High-intensity interval training increases telomere length in mice.
Animalsshort session (≤10 minute)liver10-minute HIIT regimen 3-days-a-week8 weeksfemales
Hallmarks of Aging Associate with High Intensity Interval Training Benefits and Frailty in Female C57Bl/6J Mice · The journals of gerontology. Series A, Biological sciences and medical sciences · 25 Sep 2026
Associations
6Socioeconomic position
no changein humans1
1 study
Socioeconomic position
no changein humans1
Socioeconomic position is associated with telomere length in humans (β = 0.04 [-0.01, 0.09]).
HumansCI contained the nullleukocyte
Associations between socioeconomic position index and epigenetic aging in NHANES · GeroScience · 30 Sep 2026
Multiple system atrophy
downin humans1
1 study
Multiple system atrophy
downin humans1
Multiple system atrophy is associated with telomere length in humans.
Humansblood
Preliminary insights into whole-blood mitochondrial DNA copy number and telomere length in Parkinson's disease and multiple system atrophy · Journal of neurology · 29 Sep 2026
Parkinson's disease
downin humans1
1 study
Parkinson's disease
downin humans1
Parkinson's disease is associated with telomere length in humans.
Humansblood
Preliminary insights into whole-blood mitochondrial DNA copy number and telomere length in Parkinson's disease and multiple system atrophy · Journal of neurology · 29 Sep 2026
Lithium
upin humans1
1 study
Lithium
upin humans1
Lithium is associated with telomere length in humans.
“Clinical findings further suggest that chronic lithium treatment may be associated with preserved telomere length and attenuated biological brain aging in BD.”
Reviewin BDchronic
Lithium as a Potential Senostatic Agent in Central Nervous System Aging and Bipolar Disorder · Pharmaceuticals (Basel, Switzerland) · 31 Aug 2026
Drug-induced liver injury
downin humans1
1 study
Drug-induced liver injury
downin humans1
Telomere length is associated with drug-induced liver injury in humans.
Humansin tuberculosis patientsperipheral blood mononuclear celln = 64
Telomere Length Profile and Associated Clinical Factors among Tuberculosis Patients in Indonesia · International journal of mycobacteriology · 1 Jul 2026
Diabetes mellitus
downin humans1
1 study
Diabetes mellitus
downin humans1
Telomere length is associated with diabetes mellitus in humans.
Humansin tuberculosis patientsperipheral blood mononuclear celln = 64
Telomere Length Profile and Associated Clinical Factors among Tuberculosis Patients in Indonesia · International journal of mycobacteriology · 1 Jul 2026
Latest
14Proteomic organ clocks predict mortality but trail established physiological and epigenetic biomarkers
In an older Scottish cohort, epigenetic age and brain volume outmatched plasma proteomic organ clocks for predicting long-term all-cause mortality.
Older adults with preserved cognition show slower biological aging and longer telomeres
An observational study in Chile linked perfect Mini-Mental State Examination scores in people over 80 to slower epigenetic clocks and longer estimated telomeres.
Telomere attrition marks disease severity in chronic cholestatic liver diseases
Epigenetic telomere length analysis in patients with sclerosing or biliary cholangitis reveals converging markers of accelerated biological aging.
Biological aging clocks combined with genetics improve dementia risk prediction
Adding proteomic, metabolomic, and clinical aging measures to polygenic scores boosted prediction accuracy in two large human cohorts.