Alzheimer's disease and related dementias
Disease1 paper2 findings
- Humans1
Associations
2ProtAge
upin humans1
1 study
ProtAge
upin humans1
ProtAge predicts Alzheimer's disease and related dementias in humans (sHR = 2.01, 95% CI: 1.13-3.58).
“followed by ProtAge (sHR = 2.01, 95% CI: 1.13-3.58).”
Humansin UK Biobankmedian 10.08 yearsn = 16,215
Biological aging clocks combined with genetics improve dementia risk prediction · Alzheimer's & dementia : the journal of the Alzheimer's Association · 29 Sep 2026
Polygenic risk score
upin humans1
1 study
Polygenic risk score
upin humans1
Polygenic risk score predicts Alzheimer's disease and related dementias in humans (sHR = 2.24, 95% CI: 2.02-2.48).
“PRS was the strongest predictor (subdistribution hazard ratio [sHR] = 2.24, 95% CI: 2.02-2.48)”
Humansin UK Biobankmedian 10.08 yearsn = 16,215
Biological aging clocks combined with genetics improve dementia risk prediction · Alzheimer's & dementia : the journal of the Alzheimer's Association · 29 Sep 2026
Latest
1Biological aging clocks combined with genetics improve dementia risk prediction
Adding proteomic, metabolomic, and clinical aging measures to polygenic scores boosted prediction accuracy in two large human cohorts.