Cellular senescenceReview28 Sep 2026

Lithium as a Potential Senostatic Agent in Central Nervous System Aging and Bipolar Disorder

Pharmaceuticals

Abstract · CC BY

Lithium remains the gold-standard maintenance treatment for bipolar disorder (BD) and is distinguished by its unique anti-suicidal and neuroprotective properties. Beyond its established psychiatric efficacy, growing evidence suggests that lithium may modulate fundamental mechanisms of biological aging.

The paper

Rybakowski JK, Mydlak C, Klimek N et al.

Pharmaceuticals · 31 Aug 2026

doi.org/10.3390/ph19091378 PubMed

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Lithium as a Potential Senostatic Agent in Central Nervous System Aging and Bipolar Disorder

The paper

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