Klotho–FGF23 axis

Human trial2
Animals1
Cells1

Latest

Human trial30 Sep

Exercise-induced extracellular vesicles enhance aged cartilage health via microRNA-29

A three-month aerobic program in older adults generated microRNA-29-loaded vesicles that boosted Klotho expression and enhanced cartilage health in mice.

Nature Aging · Iijima H et al.

Pharmaceutical Strategies for Translating Klotho-Based Therapeutics: From Biologic Developability to Advanced Delivery Systems

ReviewPharmaceutics

28 Sep

Characterization of Umbilical Cord Mesenchymal Stromal Cells Overexpressing Klotho and In Vitro Anti-Aging Efficacy of Their Derived Extracellular Vesicles

CellsInternational Journal of Molecular Sciences

28 Sep

Impact of a Short-term Yoga Lifestyle Programme on Circulating Serum Klotho Levels in Patients with Type 2 Diabetes: An Exploratory Study

Human trialIndian Journal of Endocrinology and Metabolism

26 Sep

Animals26 Sep

Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice

Researchers linked lower SOX2 to reduced neurotrophic factors and structural degradation in the tongue tissue of Klotho-deficient mice.

Mechanisms of Ageing and Development · Duong MD et al.