Sox2

GeneMus musculus1 paper2 findingsMGI 98364NCBI Gene 20674Taxon 10090

Animals1

Interventions

1

Kl knockout

downin mice1

1 study

Kl knockout decreases Sox2 in mice.
Animalstongue epithelium
Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice · Mechanisms of ageing and development · 24 Sep 2026

Kl knockout →

Effects

1

Ntf3

upin mouse cells1

1 study

Sox2 activates Ntf3 in mouse cells.
Cells
Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice · Mechanisms of ageing and development · 24 Sep 2026

Latest

1

Animals26 Sep

Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice

Researchers linked lower SOX2 to reduced neurotrophic factors and structural degradation in the tongue tissue of Klotho-deficient mice.

Mechanisms of Ageing and Development · Duong MD et al.