MitochondriaReview
Oxidative Stress and Mitochondrial Dysfunction in Chronic Kidney Disease: From Molecular Mechanisms to Biomarkers and Targeted Therapies
Abstract · CC BY
Chronic kidney disease (CKD) represents a major global health challenge, affecting more than 10% of the population and contributing substantially to morbidity and premature mortality.
- Chronic inflammation
- Epigenetic alterations
- Mitochondrial dysfunction
- Ferroptosis
- Mitochondrial biogenesis (PGC-1α)
- Mitophagy
- Oxidative phosphorylation
- Oxidative stress and ROS signalling
- Chronic kidney disease
- Fibrosis
- Mitochondrial DNA
- Reactive oxygen species
The paper
Oxidative Stress and Mitochondrial Dysfunction in Chronic Kidney Disease: From Molecular Mechanisms to Biomarkers and Targeted Therapies
De Luca F, Troise D, Camporeale V et al.
Antioxidants · 4 Sep 2026