Reactive oxygen species
Biomarker32 papers8 findingsMeSH D017382
In human, mouse, and spiny mouse cells, various interventions decrease reactive oxygen species. In worms, multiple treatments reduce reactive oxygen species levels, whereas musk ketone increases them.
- Animals9
- Model organisms9
- Cells3
Interventions
7M2-KC-FEV
downin mouse cells1
1 study
M2-KC-FEV
downin mouse cells1
M2-KC-FEV decreases reactive oxygen species in mouse cells.
Cellsin UVB-injured mouse keratinocytes and dermal fibroblasts
Hybrid extracellular vesicles protect mouse skin from ultraviolet B photoaging · ACS applied materials & interfaces · 1 Oct 2026
Sonnerachromones a–g
downin worms1
1 study
Sonnerachromones a–g
downin worms1
Sonnerachromones a–g decreases reactive oxygen species in worms.
Model organisms
Sonnerachromones A–C from Sonneratia Apetala Delay Aging and Extend Lifespan in Caenorhabditis elegans Associated with Modulation of Telomere–Telomerase-Related Pathways · Preprints.org · 29 Sep 2026 · Preprint
Peptone-free nematode growth medium
downin worms1
1 study
Peptone-free nematode growth medium
downin worms1
Peptone-free nematode growth medium decreases reactive oxygen species in worms.
Model organismswith PFA-killed OP50
Peptone-free nematode growth medium improves culture stability and physiological resilience in Caenorhabditis elegans · Biogerontology · 28 Sep 2026
Pimozide
downin worms1
1 study
Pimozide
downin worms1
Pimozide decreases reactive oxygen species in worms.
“pimozide-treated nematodes showed enhanced resistance to heat, ultraviolet and oxidative stress, concomitant with reduced endogenous reactive oxygen species levels.”
Model organisms
Antipsychotic drug pimozide extends lifespan and boosts stress resistance in nematodes · Antioxidants (Basel, Switzerland) · 21 Sep 2026
Telomir-zn
downin human cells1
1 study
Telomir-zn
downin human cells1
Telomir-zn decreases reactive oxygen species in human cells.
“Complementary studies in human ARPE-19 RPE cells showed attenuation of iron/copper-induced ROS and calcium dysregulation”
Cellsunder iron/copper inductionretinal pigment epithelium
Targeted metal modulation preserves retinal structure and vision in zebrafish · International journal of molecular sciences · 16 Sep 2026
Musk ketone
upin worms1
1 study
Musk ketone
upin worms1
Musk ketone increases reactive oxygen species in worms.
Model organisms0.4 to 20 mg/L24 h
Assessing the toxicological effects of synthetic musk ketone using the Caenorhabditis elegans model · BMC pharmacology & toxicology · 9 Sep 2026
Xiaoyao san
downin worms1
1 study
Xiaoyao san
downin worms1
Xiaoyao san decreases reactive oxygen species in worms.
Model organisms
[Xiaoyao San alleviates abnormal α‑syn aggregation and neuronal injury in a Caenorhabditis elegans model of Parkinson disease via the SKN-1 antioxidative pathway] · Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 1 Sep 2026
Upstream
1Acomys
downin Acomys cells1
1 study
Acomys
downin Acomys cells1
Acomys decrease reactive oxygen species in Acomys cells.
Cellsear pinna fibroblast
Spiny mouse fibroblasts prefer glycolysis and resist oxidative stress across lifespan · The Journal of biological chemistry · 24 Sep 2026
Latest
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Hybrid extracellular vesicles protect mouse skin from ultraviolet B photoaging
Vesicles fused from M2 macrophages and keratinocytes reduced oxidative stress, inflammation, and collagen degradation through the IL-4Rα/JAK/STAT3 pathway.
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Icariin improves cognition and reduces neuroinflammation by promoting mitophagy in mice
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Chelating intracellular calcium reduces fibroblast senescence and eases lung fibrosis
Treating cells and an in vivo fibrosis model with a calcium chelator delayed senescence markers, reduced collagen buildup, and dampened inflammatory secretions.