Sus scrofa

1. Leptin decreases senescence-associated beta-galactosidase in pig cells.

   Cellsunder heat stressSertoli cellmales

   Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026

2. Leptin activates autophagy in pig cells.

   Cellsunder heat stressSertoli cellmales

   Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026

3. Leptin activates MAPK/ERK signalling in pig cells.

   Cellsunder heat stressSertoli cellmales

   Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026

4. Leptin decreases genomic instability in pig cells.

   Cellsunder heat stressSertoli cellmales

   Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026

5. Leptin decreases cellular senescence in pig cells.

   Cellsunder heat stressSertoli cellmales

   Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026

Leptin →

1. Heat stress induces cellular senescence in pig cells.

   CellsSertoli cellmales

   Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026

Heat stress →

1. ANTI-MIR-128 aso protects against Duchenne muscular dystrophy in pigs.

   Animalspig model of Duchenne muscular dystrophyantisense oligonucleotidestriated muscle

   Inhibiting miR-128-3p restores muscle mass and function in aged mice · bioRxiv : the preprint server for biology · 7 Sep 2026 · Preprint

ANTI-MIR-128 aso →