Salvianolic acid a
Intervention1 paper2 findingsPubChem 5281793ChEBI 9017
- Animals1
Outcomes
2Atherosclerosis
downin mice1
1 study
Atherosclerosis
downin mice1
Salvianolic acid a protects against atherosclerosis in mice.
“decreased the size of plaque, and increased the stability of the fibrous cap.”
Animalsin ApoE -/- mice fed a high-fat diet
Salvianolic acid A eases atherosclerosis in mice by eliminating senescent vascular cells · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
Salvianolic acid a decreases cellular senescence in mice.
“In ApoE -/- mice, SAA reduced the burden of senescent VSMCs, decreased the size of plaque, and increased the stability of the fibrous cap.”
Animalsin ApoE -/- mice fed a high-fat dietvascular smooth muscle cell
Salvianolic acid A eases atherosclerosis in mice by eliminating senescent vascular cells · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Latest
1Salvianolic acid A eases atherosclerosis in mice by eliminating senescent vascular cells
The compound disrupts an HSP90α complex to trigger endoplasmic reticulum stress and selectively induce apoptosis in senescent smooth muscle cells.