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Mitomycin c

Intervention1 paper3 findingsPubChem 5746ChEBI 27504

  • Cells1

Outcomes

3

Mitochondrial dysfunction

no changein human cells1

1 study
  1. Mitomycin c has no effect on mitochondrial dysfunction in human cells.

    Cellsumbilical cord mesenchymal stem cell1.5 μg/mL7 days

    Stress-Induced Senescence of Human Umbilical Cord Mesenchymal Stromal Cells Caused by Mitomycin C · Bulletin of experimental biology and medicine · 28 Sep 2026

Mitochondrial dysfunction →

Senescence-associated secretory phenotype (SASP)

upin human cells1

1 study
  1. Mitomycin c increases senescence-associated secretory phenotype (SASP) in human cells.

    Cellsumbilical cord mesenchymal stem cell1.5 μg/mL7 days

    Stress-Induced Senescence of Human Umbilical Cord Mesenchymal Stromal Cells Caused by Mitomycin C · Bulletin of experimental biology and medicine · 28 Sep 2026

Senescence-associated secretory phenotype (SASP) →

p53–p21 pathway

upin human cells1

1 study
  1. Mitomycin c activates p53–p21 pathway in human cells.

    Cellsumbilical cord mesenchymal stem cell1.5 μg/mL7 days

    Stress-Induced Senescence of Human Umbilical Cord Mesenchymal Stromal Cells Caused by Mitomycin C · Bulletin of experimental biology and medicine · 28 Sep 2026

p53–p21 pathway →

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