Stress-Induced Senescence of Human Umbilical Cord Mesenchymal Stromal Cells Caused by Mitomycin C
- Mitomycin c
- Cellular senescence
- Genomic instability
- Mitochondrial dysfunction
- DNA damage response
- Mitochondrial biogenesis (PGC-1α)
- Senescence-associated secretory phenotype (SASP)
- p53–p21 pathway
- CDKN1A
- CDKN1B
- COL1A1
- CXCL8
The paper
Stress-Induced Senescence of Human Umbilical Cord Mesenchymal Stromal Cells Caused by Mitomycin C
Safonova EI, Romanov YA, Tyrina EA
Bulletin of Experimental Biology and Medicine · 28 Sep 2026