Il1b

GeneMus musculus5 papersMGI 96543NCBI Gene 16176Taxon 10090

Animals5

Latest

Gastrodia elata polysaccharide extends worm lifespan and mitigates age-related deficits in mice

The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.

Food Science & Nutrition · Shi H et al.

AnimalsMitochondria1 Oct

Icariin improves cognition and reduces neuroinflammation by promoting mitophagy in mice

The flavonoid engages PINK1 to curb microglial pyroptosis and mitochondrial stress in models of Alzheimer's disease.

Chinese Journal of Natural Medicines · Fan L et al.

AnimalsMitochondria28 Sep

Astragaloside IV reduces cardiac aging in mice by restoring mitochondrial balance

The compound lowered senescence markers and improved heart function through SIRT3-driven DRP1 deacetylation in aged mice and cultured cardiomyocytes.

FASEB Journal · Chen X et al.

Alda-1 Alleviates the Cognitive Deficits in D-galactose-induced Aging Mice by Regulating Oxidative Stress, Neuroinflammation, and Mitochondrial Biogenesis

AnimalsThe Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

26 Sep

AnimalsCellular senescence26 Sep

Lack of the AT2R receptor accelerates cardiac senescence and fibrosis in aging mice

Mice lacking the receptor also showed higher inflammation, elevated DNA damage, and a five-month reduction in median lifespan.

Clinical Science (London, England · Zacarias-Rodrigues LM et al.