Cardiac fibrosis

Disease2 papers1 finding

Animals1

Upstream

1

Loss of chromosome Y

upin mice1

1 study

Loss of chromosome Y induces cardiac fibrosis in mice.
Reviewhematopoietic systemmales
Mosaic Loss of Chromosome Y (LOY): From Genomic Instability to Disease and Single-Cell Detection · Frontiers in bioscience (Landmark edition) · 1 Sep 2026

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Latest

2

Mosaic Loss of Chromosome Y (LOY): From Genomic Instability to Disease and Single-Cell Detection

ReviewFrontiers in Bioscience

30 Sep

AnimalsCellular senescence26 Sep

Lack of the AT2R receptor accelerates cardiac senescence and fibrosis in aging mice

Mice lacking the receptor also showed higher inflammation, elevated DNA damage, and a five-month reduction in median lifespan.

Clinical Science (London, England · Zacarias-Rodrigues LM et al.