Aneuploidy
Disease1 paper
Latest
4HumansPreprint
Inherited genetic variants influence age-associated mosaic chromosomal errors in human blood
A large genomic analysis reveals over 800 inherited variants and structural features that alter how frequently chromosomes missegregate in aging individuals.
AnimalsPreprint
TET enzyme deficiency drives the selection of specific aneuploid cells in mice
Loss of DNA methylation regulators accelerates clonal expansion by enriching rare pre-existing chromosomal gains such as chromosome 17 trisomy.