Ferrous iron
Biomarker2 papers
- Animals1
- Model organisms1
Latest
2Model organismsMitochondria
Targeted metal modulation preserves retinal structure and vision in zebrafish
Telomir-Zn depleted labile iron, lowered oxidative stress, and improved visual behaviors and epigenetic marks in zebrafish and cultured human retinal cells.
AnimalsNAD+ & sirtuins
Activating Sirt1 reduces aortic valve calcification in mice and human cells
The sirtuin protects valves by activating the Nrf2 pathway, preserving mitochondrial function, and preventing iron-driven ferroptosis.