Epigenetic clocks
Biomarker1 paper1 finding
- Humans1
Associations
1Epigenetic puberty
upin humans1HR 0.13–0.47
1 study
Epigenetic puberty
upin humans1HR 0.13–0.47
Epigenetic puberty is associated with epigenetic clocks in humans (standardized coefficients: HRS, 0.13 to 0.47; GS, 0.05 to 0.40).
Humansage-residualized
Epigenetic puberty index tracks biological aging and adult health risks · medRxiv · 30 Sep 2026 · Preprint
Latest
11Early life stress accelerates epigenetic aging in zebra finches
Corticosterone treatment shifts DNA methylation profiles in young chicks toward those of older birds and reshapes longevity pathways.
Proteomic organ clocks predict mortality but trail established physiological and epigenetic biomarkers
In an older Scottish cohort, epigenetic age and brain volume outmatched plasma proteomic organ clocks for predicting long-term all-cause mortality.
Blood cell composition explains substantial variation in DNA methylation age
Cell counts explain less variation in age acceleration and only modestly affect its links to mortality and 176 incident health outcomes.
Epigenetic puberty index tracks biological aging and adult health risks
A DNA-methylation measure of pubertal development correlates with established epigenetic clocks and predicts mortality and disease in two large adult cohorts.
Exercise slows epigenetic aging in breast cancer survivors
A randomized trial shows a 12-month workout program slowed DNA methylation clocks and linked with preserved cognitive health.
Older adults with preserved cognition show slower biological aging and longer telomeres
An observational study in Chile linked perfect Mini-Mental State Examination scores in people over 80 to slower epigenetic clocks and longer estimated telomeres.
Accelerated epigenetic aging predicts major depression and brain changes after trauma
Emergency department measurements of GrimAge and DunedinPACE biological aging markers tracked subsequent depressive symptoms and neural connectivity shifts in adults over 35.