ML385
Intervention2 papersPubChem 1383822
- Animals2
Latest
2Animals
4-Octyl itaconate restores parotid gland function in aging mice
The itaconate derivative reduces fibrosis and lipid buildup while curbing oxidative stress through AMPK signaling pathways.
AnimalsNAD+ & sirtuins
Activating Sirt1 reduces aortic valve calcification in mice and human cells
The sirtuin protects valves by activating the Nrf2 pathway, preserving mitochondrial function, and preventing iron-driven ferroptosis.