MDIVI-1
Intervention3 papers1 findingPubChem 3825829ChEBI 232380
- Animals2
- Cells1
Outcomes
1Muscle atrophy
downin mice1
1 study
Muscle atrophy
downin mice1
MDIVI-1 decreases muscle atrophy in mice.
“Mdivi-1 treatment produced similar protective effects, including attenuation of skeletal muscle atrophy, oxidative stress, and inflammatory responses.”
AnimalsHFD-fed miceskeletal muscle
Aerobic Exercise Attenuates High-Fat Diet-Induced Skeletal Muscle Atrophy by Suppressing Oxidative Stress, Inflammation, and Drp1-Associated Mitochondrial Fission · Antioxidants (Basel, Switzerland) · 31 Aug 2026
Latest
3AnimalsMitochondria
Icariin improves cognition and reduces neuroinflammation by promoting mitophagy in mice
The flavonoid engages PINK1 to curb microglial pyroptosis and mitochondrial stress in models of Alzheimer's disease.
CellsMitochondria
FUNDC1 protects skin against UVA damage through mitophagy and P53 stability
Researchers identified a molecular pathway where FUNDC1 preserves mitochondrial quality and works with BAZ1B to regulate P53 during skin photoaging.