DEPP1 overexpression
Intervention1 paper1 finding
- Animals1
Outcomes
1Muscle atrophy
upin mice1
1 study
Muscle atrophy
upin mice1
DEPP1 overexpression induces muscle atrophy in mice.
Animalsskeletal muscle overexpressionskeletal muscle
Depp1 drives muscle loss under fasting and low oxygen in mice · bioRxiv · 27 Sep 2026 · Preprint
Latest
1Depp1 drives muscle loss under fasting and low oxygen in mice
The study reveals that the protein localizes to mitochondria to regulate autophagy and mitochondrial degradation during nutrient and oxygen limitation.