DEPP1 knockout
Intervention1 paper1 finding
- Animals1
Outcomes
1Muscle atrophy
downin mice1
1 study
Muscle atrophy
downin mice1
DEPP1 knockout decreases muscle atrophy in mice.
Animalsunder fasting and hypoxiawhole-body knockoutskeletal muscle
Depp1 drives muscle loss under fasting and low oxygen in mice · bioRxiv · 27 Sep 2026 · Preprint
Latest
1Depp1 drives muscle loss under fasting and low oxygen in mice
The study reveals that the protein localizes to mitochondria to regulate autophagy and mitochondrial degradation during nutrient and oxygen limitation.