Ccnd2
GeneMus musculus1 paper1 findingMGI 88314NCBI Gene 12444Taxon 10090
- Animals1
Effects
1Senescence-associated secretory phenotype (SASP)
upin mouse cells1
1 study
Senescence-associated secretory phenotype (SASP)
upin mouse cells1
Ccnd2 increases senescence-associated secretory phenotype (SASP) in mouse cells.
Cellsmacrophage
A distinct p21-driven macrophage senotype accumulates during aging and liver disease · bioRxiv · 28 Sep 2026 · Preprint
Latest
1A distinct p21-driven macrophage senotype accumulates during aging and liver disease
Researchers identified a p53-p21-Cyclin D2 axis that governs senescent macrophages in mice and human liver cirrhosis and can be cleared with senolytics.