Depression
Disease1 paper
- Animals1
Latest
2Accelerated epigenetic aging predicts major depression and brain changes after trauma
Emergency department measurements of GrimAge and DunedinPACE biological aging markers tracked subsequent depressive symptoms and neural connectivity shifts in adults over 35.
AnimalsmTOR & rapamycin
Chronic stress accelerates Alzheimer pathology in mice by hyperactivating mTORC1
Inhibiting mTORC1 restored autophagy, reduced amyloid accumulation, and corrected circuit desynchronization and behavioral deficits in stressed Alzheimer model mice.