Age-related macular degeneration

Disease3 papers1 finding

Model organisms1
Cells1

Associations

Oxidative stress and ROS signalling

upin humans1

1 study

Oxidative stress and ROS signalling is associated with age-related macular degeneration in humans.
“oxidative stress has emerged as one of the most plausible links connecting retinal degeneration and cardiovascular pathology.”
Reviewretina
From Retina to Vasculature: Oxidative Stress as a Common Mechanistic Link Between Age-Related Macular Degeneration and Cardiovascular Disease · Antioxidants (Basel, Switzerland) · 9 Sep 2026

Oxidative stress and ROS signalling →

Latest

Dioscin attenuates D‑galactose‑induced retinal pigment epithelium senescence and epithelial-mesenchymal transition via the TGF‑β2/PI3K/Akt/β‑catenin pathway

CellsPloS One

29 Sep

Model organismsMitochondria28 Sep

Targeted metal modulation preserves retinal structure and vision in zebrafish

Telomir-Zn depleted labile iron, lowered oxidative stress, and improved visual behaviors and epigenetic marks in zebrafish and cultured human retinal cells.

International Journal of Molecular Sciences · Angel I et al.

From Retina to Vasculature: Oxidative Stress as a Common Mechanistic Link Between Age-Related Macular Degeneration and Cardiovascular Disease

ReviewAntioxidants

26 Sep