Cellular senescenceCells29 Sep 2026

Dioscin attenuates D‑galactose‑induced retinal pigment epithelium senescence and epithelial-mesenchymal transition via the TGF‑β2/PI3K/Akt/β‑catenin pathway

PloS One

Abstract · CC BY

Purpose This study aimed to evaluate the protective effects of Dioscin in an age-related macular degeneration (AMD) -like model and to explore its potential therapeutic mechanisms.

The paper

Ouyang Q, Zhou H, Ji C et al.

PloS One · 28 Sep 2026

doi.org/10.1371/journal.pone.0359423 PubMed

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Dioscin attenuates D‑galactose‑induced retinal pigment epithelium senescence and epithelial-mesenchymal transition via the TGF‑β2/PI3K/Akt/β‑catenin pathway

The paper

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