C-reactive protein
Biomarker3 papers2 findings
- Humans2
Interventions
1Exercise
downin humans1
1 study
Exercise
downin humans1
Exercise decreases C-reactive protein in humans.
Human trial8 weeks to 12 months
Impact of supervised physical exercise on inflammatory and oxidative stress biomarkers in older adults: a systematic review and meta-analysis of randomized controlled trials · The Gerontologist · 24 Sep 2026
Associations
1PhenoAge
upin humans1
1 study
PhenoAge
upin humans1
C-reactive protein is associated with PhenoAge in humans.
“CRP, BMI, alcohol methylation, and AHRR/cg05575921 were positively associated with the early-life systemic dysregulation domain”
Humansearly-life systemic dysregulation domainblood
Blood methylation clocks capture two distinct biological domains of aging · Genes · 9 Sep 2026
Latest
3Mechanistic biological age clock matches PhenoAge in predicting human mortality
The systems pharmacology model splits biological age into organ axes, revealing that pharmacological drops in inflammation may not translate to expected risk reductions.
Blood methylation clocks capture two distinct biological domains of aging
Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle exposures.