Brain agingReview28 Sep 2026

An intestine-centric view of neurodegeneration: How intestine-derived signals mediate the intestine-brain axis to impact Alzheimer's disease

Journal of Neuroimmunology

The paper

Shen S, Zhou Y, Qian J et al.

Journal of Neuroimmunology · 23 Sep 2026

doi.org/10.1016/j.jneuroim.2026.579102 PubMed

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An intestine-centric view of neurodegeneration: How intestine-derived signals mediate the intestine-brain axis to impact Alzheimer's disease

The paper

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Human neurons accumulate far more mutations over lifespan than shorter-lived mammals

CAR T cells targeting inflammatory bone marrow progenitors restore cognition in aged mice

Extracellular cGAMP drives neuroinflammation and premature aging phenotypes in mice

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