Schizosaccharomyces pombe
Organism2 papers2 findingsTaxon 4896
- Model organisms2
Interventions
2Compound 991
uplifespan1
1 study
Compound 991
uplifespan1
Compound 991 extends lifespan in fission yeast.
Model organisms
Direct AMPK activation extends lifespan across yeast, worms, and flies · Aging cell · 30 Sep 2026
SOD2 proximal apa site mutation
upmitochondrial dysfunction1
1 study
SOD2 proximal apa site mutation
upmitochondrial dysfunction1
SOD2 proximal apa site mutation increases mitochondrial dysfunction in fission yeast cells.
Cellsin a mitophagy-deficient (atg43Δ) background
Alternative polyadenylation regulates mitochondrial sod2 during yeast quiescence transitions · bioRxiv · 28 Sep 2026 · Preprint
Latest
2Direct AMPK activation extends lifespan across yeast, worms, and flies
Treatment with the direct activator 991 also induced a pro-longevity proteomic profile in mice.
Alternative polyadenylation regulates mitochondrial sod2 during yeast quiescence transitions
Researchers mapped dynamic changes in transcript untranslated regions during quiescence in fission yeast, identifying an RNA-processing pathway that controls mitochondrial maintenance.