Tet2/3 deletion
Intervention1 paper2 findings
- Animals1
Outcomes
1Lymphoid expansion
upin mice1
1 study
Lymphoid expansion
upin mice1
Tet2/3 deletion induces lymphoid expansion in mice.
Animalsinvariant natural killer T cell
TET enzyme deficiency drives the selection of specific aneuploid cells in mice · bioRxiv · 1 Oct 2026 · Preprint
Associations
1Genomic instability
upin mice1
1 study
Genomic instability
upin mice1
Tet2/3 deletion is associated with genomic instability in mice.
Animalsfollowing transplantation into recipient miceinvariant natural killer T cell
TET enzyme deficiency drives the selection of specific aneuploid cells in mice · bioRxiv · 1 Oct 2026 · Preprint
Latest
1AnimalsPreprint
TET enzyme deficiency drives the selection of specific aneuploid cells in mice
Loss of DNA methylation regulators accelerates clonal expansion by enriching rare pre-existing chromosomal gains such as chromosome 17 trisomy.