Sodium arsenite
Intervention1 paper3 findings
- Animals1
Outcomes
3p53–p21 pathway
upin rat cells1
1 study
p53–p21 pathway
upin rat cells1
Sodium arsenite activates p53–p21 pathway in rat cells.
Cells
Arsenic triggers heart senescence in mice while quercetin counteracts the damage · Toxicology and applied pharmacology · 26 Sep 2026
Cellular senescence
upin rat cells1
1 study
Cellular senescence
upin rat cells1
Sodium arsenite induces cellular senescence in rat cells.
Cells6 μM24 h
Arsenic triggers heart senescence in mice while quercetin counteracts the damage · Toxicology and applied pharmacology · 26 Sep 2026
Left ventricular systolic and diastolic dysfunction
upin mice1
1 study
Left ventricular systolic and diastolic dysfunction
upin mice1
Sodium arsenite increases left ventricular systolic and diastolic dysfunction in mice.
Animalsmyocardium10 or 20 mg/L6 weeksmales
Arsenic triggers heart senescence in mice while quercetin counteracts the damage · Toxicology and applied pharmacology · 26 Sep 2026
Latest
1Arsenic triggers heart senescence in mice while quercetin counteracts the damage
Exposure to environmental arsenic caused heart dysfunction via the p53 and p21 pathway, which quercetin treatment reversed in cultured rat cardiomyoblasts.